| abstract |
Compounds of the formula ##STR1## wherein R 1 is ##STR2## the asterisk denotes the specific bonding orientation to the piperidine moiety; R 2 is alkylene or --CO--(CH 2 ) n -- wherein n is 0 to 11; R 3 and R 4 , independently, are hydrogen, halogen or lower alkoxy; and HET is pyridinyl, pyrimidinyl or imidazolyl, and salts thereof with pharmaceutically acceptable acids, are described. The compounds of formula I exhibit insulin lowering activity and are useful as antiobesity agents. |