http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4628057-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 |
| filingDate | 1984-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1986-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb5ae8382be3618ccf46215694818b69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_554504249d9eb92fb66fd4f0873a6031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38b2497f5b7d86346120d0b9b5925870 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66ef83726131f116868ae1901ee7a038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57d2c924544d6b4df298933accad687e |
| publicationDate | 1986-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4628057-A |
| titleOfInvention | Tetrahydro-β-carboline derivatives and treatment of liver diseases |
| abstract | Novel tetrahydro- beta -carboline derivatives of the formula: <IMAGE> wherein R1 is carboxyl, a lower alkoxycarbonyl, carbamoyl, an N,N-di-lower alkylcarbamoyl, an N-(phenyl-substituted lower alkylidenamino)carbamoyl, a [N,N-di(lower alkyl)amino]-lower alkyl, or a nitrogen-containing monocyclic heterocyclic group; R2 is hydrogen atom, a lower alkyl, or a hydroxy-lower alkyl group, or R2 is combined with R1 to form a group: -CO-O-CH2-; R3 is hydrogen atom, a lower alkyl, a phenyl-lower alkyl, or a group: -CSS-R4; R4 is hydrogen atom, an alkyl, or a group: -(CH2)nY1; n is 0, 1 or 2, Y1 is a lower alkenyl, a phenyl-substituted lower alkenyl, an N,N-di(lower alkyl)amino, a lower alkylmercapto, a lower alkoxycarbonyl, benzoyl, naphthyl, a cycloalkyl, a monocyclic heterocyclic group, or a substituted or unsubstituted phenyl, which have excellent activities for alleviating, curing and preventing hepatic damages and are useful as a therapeutic or prophylactic agent for hepatic diseases, and processes for the preparation thereof, and a pharmaceutical composition containing the above compound as an active ingredient. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009227619-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004106335-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8772311-B2 |
| priorityDate | 1983-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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