abstract |
Pharmaceutical preparations having an antiphlogistic action are described. The preparations contain, as active ingredient, a benzazole derivative corresponding to the general tautomeric formulae I <IMAGE> (I) wherein X represents a sulphur or oxygen atom and R1 represents a hydrogen atom and R2 a hydroxymethyl, formyl, lower carbalkoxy or lower acyl group or R1 and R2 together represent the group <IMAGE> wherein R3 and R4 denote, independently of one another, a hydrogen atom or a C1-C6-alkyl group, or they contain a physiologically acceptable salt thereof. These pharmaceutical preparations are suitable in particular for the treatment of inflammatory conditions and for inhibiting the lipoxygenase and/or cyclooxygenase route of arachidonic acid metabolism. |