http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4599444-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-487 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C61-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C61-37 |
| filingDate | 1984-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1986-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6413a0637c274a0fac0e8a08b6436ef3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0945a84ad1c94401ca2c78c3b3f51bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_752c944b4d09de6dcadbf6060b37c373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecb94c5d63e94331f4d2d0995394fdcc |
| publicationDate | 1986-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4599444-A |
| titleOfInvention | Process for the separation of isomeric cyclopropane-carboxylic acids |
| abstract | The invention relates to a new process for separating the four stereoisomers of the cyclopropanecarboxylic acids of the formula ##STR1## wherein R stands for a methyl group or a halogen atom. n The process comprises n reacting a salt formed with an alkali hydroxide or an alkali carbonate of dl-cis-trans-2,2-dimethyl-3-(2,2-disubstituted vinyl)-cyclopropanecarboxylic acids containing the isomers in any ratio or the pure dl-cis and dl-trans-2,2-dimethyl-3-(2,2-disubstituted vinyl)-cyclopropanecarboxylic acids prepared therefrom by the means of a selective dissolution with aromatic and aliphatic hydrocarbon solvents (suitably with benzene, extraction petroleum ether, n-hexane) with N-benzyl-2-aminobutanol enantiomers or with the hydrochlorides thereof in an aqueous medium or aqueous acetone medium, obtaining the crystalline diastereomeric salt from the solution by filtration, decomposing said salt by using a mineral acid, then separating the thus obtained optically active cyclopropanecarboxylic acid n and obtaining the other isomer or other mixture of isomers from the filtrate of the said diastereomeric salt similarly after acidifying by a mineral acid, if desired, purifying the said optically active 2,2-di-methyl-3-(2,2-disubstituted vinyl)-cyclopropane-carboxylic acid isomers obtained by the above-mentioned procedure by a selective precipitation and recovering the resolving agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4843174-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4845272-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4874473-A |
| priorityDate | 1983-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.