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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-482
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-482
filingDate 1984-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1986-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca5b73bf0ccd1934a2132d4b13db5b7a
publicationDate 1986-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4595592-A
titleOfInvention Process for obtaining laxative compounds from senna drugs
abstract The present invention provides a process for obtaining laxative compounds from senna drug, wherein n (a) the senna drug is extracted with aqueous methanol by countercurrent percolation and the extract concentrated at a temperature of ≦50° C. until the methanol has been completely removed from the extract; n (b) the extract obtained is purified by continuous liquid-liquid extraction with an organic solvent; n (c) the refined material (raffinate) obtained is transferred to a crystallization apparatus, acidified, while stirring, to a pH of 1.5 to 2.0, seeded with sennoside crystals, left to crystallize while stirring and the crystalline crude sennoside obtained separated off; n (d) whereafter, the crude sennoside are, if desired, recrystallized and optionally converted with a pharmacologically compatible base into a pharmacologically compatible salt.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100429086-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5574151-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5232699-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011014976-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2650507-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5710260-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5514663-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008135115-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5397573-A
priorityDate 1984-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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