http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4588831-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebccbd4604bd7c6c0b160a3fc6b829bb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0093 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 |
filingDate | 1984-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1986-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20600ee46e2d5455cfa9cd81606c7f54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63d9637fd6364030634b76a5aa9a1d3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d25ca66e84794351f7e6be5d909b18e |
publicationDate | 1986-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4588831-A |
titleOfInvention | Platinum complex compounds of substituted 5,8-dihydroxyl-1,4-naphthoquinone, and process for their production and use |
abstract | The invention relates to platinum complexes of the following general formula: <IMAGE> (I) wherein R1 and R2 represent alkyl radicals with 1 to 18 carbon atoms, or R1 or R2 represent a hydrogen atom and R2 or R1 can represent an alkyl radical or a <IMAGE> in which R3 is a hydrogen atom or the <IMAGE> radical or an acyl radical, and x=1 or 2. These compounds can be produced by reaction of an alcohol solution of a 5,8-dihydroxyl-1,4-naphthoquinone of the following formula: <IMAGE> (IV) in which the substituents R1 and R2 have the aforementioned meanings, in the presence of a concentrated aqueous ammonia solution, which adjusts the pH over 7, with K2PtCl4 at room temperature. These platinum complex compounds are characterized by a good antitumor effect with low toxicity. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002055666-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0337459-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2075014-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0337459-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2181704-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4732893-A |
priorityDate | 1984-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.