| abstract |
Therapeutic process for treating the negative symptoms of schizophrenia in humans comprising the systematic administration of a compound of the formula <IMAGE> Formula I X is a member selected from the group consisting of -H, -CH3, and -CH2-O-R; wherein R is hydrogen, alkyl of from 1 to 3 carbon atoms, inclusive, <IMAGE> or <IMAGE> wherein n is 0 to 16, inclusive, and m is 1 to 16 inclusive; Y is hydrogen or, provided when Z is hydrogen and X is CH3, hydroxy; Z is hydrogen or, provided when Y is hydrogen and X is -CH3, chloro; including the N-oxides and pharmacologically acceptable acid addition salts thereof in combination with a pharmaceutical carrier. |