| abstract |
New phospholipid derivatives represented by the formula: <IMAGE> (I) wherein R1 is alkyl, alkoxy, alkylthio or alkylsulfonyl; R2 is hydrogen, hydroxy, alkoxy, lower alkanoyloxy or lower alkylcarbamoyloxy; n is 0 or 1; R3 is hydroxy or protected hydroxy; and R4 is lower alkoxy or lower alicyclic-oxy group which is substituted with 2 or more hydroxy or protected hydroxy groups, and may be substituted with lower alkoxy or another alicyclic-oxy group having two or more hydroxy or protected hydroxy groups, in which the alicyclic ring may contain an oxygen atom; and pharmaceutically acceptable salt thereof, which exhibit antitumor activity. |