http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4555579-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76195fd1cd08192222699d8e7a88c231 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6558 |
filingDate | 1983-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1985-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eca5f2966026749befeb4efcaa9cd5a |
publicationDate | 1985-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4555579-A |
titleOfInvention | Dioxolenylmethyl ester prodrugs of phosphinic acid ace inhibitors |
abstract | Angiotensin converted enzyme inhibitor activity if exhibited by compounds having the formula ##STR1## and salts thereof wherein R 1 is hydrogen, aryl, or heteroaryl; R 2 is hydrogen, amino, alkanoylamino, arylcarbonylamino, or heteroarylcarbonylamino; n R 3 is hydrogen, alkyl, or aminoalkyl; n R 4 and R 5 are the same or different and each is hydrogen, alkyl, halogen, aryl, arylalkyl, hydroxy, alkoxy, alkylthio, aryloxy, arylthio, or cycloalkyl, or R 4 and R 5 taken together are oxo, ethylenedithio or propylenedithio; n one of R 6 and R 7 is ##STR2## and the other is hydrogen, alkyl or arylalkyl; R 8 is hydrogen, alkl or aryl; n R 9 is hydrogen or alkyl; n n is 0 or an integer of 1 to 8; n m is 0 or 1; and n A is --(CH 2 ) p --wherein p is 0 or 1, --NH--, or --O--. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6015912-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4694006-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4634689-A |
priorityDate | 1983-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 155.