| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a333e6344b62fb21a7c1ee592b165fca |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-86 |
| filingDate |
1983-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1985-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e640025f2247cc334556c61728f2d49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b04e2f0779602a9a24e783f000ffdcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8287e73549d769a586ce9193621e87bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b83a308a8586e2e0dc25b0ed674a9992 |
| publicationDate |
1985-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4528135-A |
| titleOfInvention |
Process for the preparation of penicillanic acid 1,1-dioxides |
| abstract |
A process for the preparation of penicillanic acid-1,1-dioxides of the formula <IMAGE> II wherein X is selected from the group consisting of hydrogen and substituent such as halogen or acetoxy and R is selected from the group consisting of hydrogen, a pharmaceutically acceptable metal ion and/or ester radical comprising debrominating a 6- alpha -bromo- and/or 6,6-dibromo-penicillanic 1,1-dioxide selected from the group consisting of the formula <IMAGE> III and <IMAGE> IV wherein X and R have the above definition in an aqueous containing medium with zinc in association with an acid having a pKa-value measured in water less than 3.5 and optionally if R is H converting the acid into a pharmaceutically acceptable salt or ester. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101768035-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101768035-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5801150-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4760058-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8706230-A1 |
| priorityDate |
1982-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |