abstract |
A compound of the formula: <IMAGE> where X is <IMAGE> +TR <IMAGE> and R is hydroxy, or an alkoxy with 0 or 1 hydroxy substituent, or aroxy with 0 or 1 hydroxy substituent, or alkoxy monosubstituted phenoxy, or NR1R2 where R1 is hydrogen, or an alkyl or aryl with 0 or 1 hydroxy substituent, and R2 is an alkyl or aryl with 0 or 1 hydroxy substituent. These compounds are useful as chemopreventive agents for inhibiting tumor promotion in ephithelial cells and for treating nonmalignant skin disorders. |