| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-828
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-85 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 |
| filingDate |
1983-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1985-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ffa3ca6285c988e8a55fdaa2b79794e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_057fc38a66ffa625fd1e1562ff3b55c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8807f462d17e90914d5c7fb6a6cba15 |
| publicationDate |
1985-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4510131-A |
| titleOfInvention |
Purified Mullerian Inhibiting Substance and method of use |
| abstract |
A process for purifying Mullerian Inhibiting Substance (MIS) from testicular tissue which comprises incubating testicular tissue in a culture media in the presence of a protease inhibitor in order to extract MIS from the tissue, chromatographing the extract on an anionic exchange resin followed by chromatographing the biologically active product obtained therefrom on a cationic exchange resin; the biologically active material from the cationic exchange resin is chromatographed by lectin affinity chromatography on wheat germ lectin and then either chromatographed by lectin affinity chromatography on concanavalin A or by triazinyl dye affinity chromatography on a appropriate triazinyl dye; MIS is obtained in 8,000-fold and 15,000-fold purification over original testicular tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5547854-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5661126-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5496800-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5484768-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5310880-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H06133793-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2541761-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004086497-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8906695-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7078032-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5047336-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5427780-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4753794-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6692738-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4740306-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5196334-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9218152-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005171016-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5538892-A |
| priorityDate |
1981-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |