http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4508719-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22c3adadb5cc72c5069c682947605aac |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 |
| filingDate | 1983-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1985-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3b1ae750e454990601e6377a4862260 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55ff845bb7139c911e40fbdea2e0460c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5829794a1c8bdf98c8f1c9cb58450afa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4ff1ed7df3d7a1bdfee50b244b18186 |
| publicationDate | 1985-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4508719-A |
| titleOfInvention | Hydroxyimino and alkoxyimino derivatives of 1,4-dihydropyridine and anti-hypertensive compositions |
| abstract | Compounds of formula I: <IMAGE> (I) are described in which R1 is a linear or branched alkyl radical containing between 1 and 5 carbon atoms, the alkyl radical being unsubstituted or substituted by an alkoxy group; R2 is an unsubstituted phenyl of phenyl substituted by a nitro group; R3 is hydrogen or a linear or branched alkyl residue containing between 1 and 4 carbon atoms, the alkyl radical being unsubstituted or substituted by at least one alkoxy or fluorine atom or both alkoxy and fluorine atoms; R4 is hydrogen or a linear or branched alkyl containing between 1 and 4 carbon atoms, the alkyl radical being unsubstituted or substituted by alkoxy, carbalkoxy, dialkylamino, 1-aryl or 1-heteroarylpiperazinyl, aryl or a monocyclic 5 or 6 membered heterocycle in which at least one of the heteroatoms is N,O,S such as 1-piperidinyl, 4-morpholinyl or R4 is alkenyl or cyclo(C3-C6)alkyl; and enantiomers, racemates, diastereoisomers and isomers (E) and (Z) and their salts with pharmaceutically acceptable acids. The novel compounds exhibit calcium-antagonistic activity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4833150-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4849436-A |
| priorityDate | 1982-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 173.