| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e660bc5d083a5289e036517d7cb201c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-28 |
| filingDate |
1983-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1985-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a12b7e1d0fe524df023c0ae667feb62 |
| publicationDate |
1985-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4499286-A |
| titleOfInvention |
Derivatives of thienylacetic acid amides and their pharmaceutically acceptable acid salts and a process for the preparation thereof |
| abstract |
Novel derivatives of thienylacetic acid amides of the general formula ##STR1## in which the two nitrogens on the cyclohexane ring are transconnected, the basic acetic acid amide radical is in position 2 or 3 of the thiophene nucleus, R is C 1 -C 3 alkyl, R 1 and R 2 are independently C 1 -C 3 -alkyl or represent together with the nitrogen atom to which they are attached a pyrrolidine or piperidine ring and X and Y are independently hydrogen, chlorine or bromine in position 2 to 5 of the thiophene nucleus in dependence on the position of the basic acetic acid amide group, and their pharmaceutically acceptable acid addition salts are μ-specific analgetics, which do not cause any physical dependence. Therefore, they are suitable for protracted treatment of pain conditions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5229414-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE33906-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5317028-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5063242-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5369105-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4801585-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5010085-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0393696-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5043350-A |
| priorityDate |
1982-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |