| abstract |
A tissue-equivalent, useful in the treatment of burns or other skin wounds and in the fabrication of prostheses, is disclosed which is prepared from a hydrated collagen lattice contracted by a contractile agent, such as fibroblast cells or blood platelets, to form tissue-equivalent. In one embodiment, a skin-equivalent can be fabricated by growing a layer of keratinocyte cells thereon. Both the keratinocyte cells and contractile agent may be derived from the potential recipient of the skin-equivalent. |