abstract |
The disclosure relates to novel synthetic peptide substrates having high activity for the enzyme collagenase. These substrates have the following amino acid sequences: n n R.sub.1 -Pro-Leu-Gly-Leu-Leu-Gly-R.sub.2 n n and n n R.sub.1 -Pro-Leu-Gly-Leu-Ala-Gly-R.sub.2, n n wherein n R 1 =H or N-protecting group, and n R 2 =terminal amide, carboxyl or ester group. |