http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4464532-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e43b4ca6b41ce9f54c9a895d474c81a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-32 |
| filingDate | 1982-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fc58e34c850d177608bfefb93865d6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73e831daf586dc7a5f07575fb5ff3ba3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0ea93e0222170646cc66735bdb34a69 |
| publicationDate | 1984-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4464532-A |
| titleOfInvention | Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone |
| abstract | A novel process for producing 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone, and its intermediates. 7-Alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone can be obtained by reacting substituted methylenetriphenylphosphorane with 3,5-dimethyl-4-alkoxycarbonylphthalic anhydride to obtain 6-alkoxycarbonyl-5,7-dimethyl-Δ 3 ,α -substituted methylenephthalide, reacting the latter with hydrazine to obtain a phthalazone derivative, hydrolyzing the latter, halogenating the hydrolyzate to obtain 7-alkoxycarbonyl-6,8-dimethyl-4-(α-halogeno-α-substituted methyl)-1-phthalazone and then directly hydrolyzing and decarboxylating the latter or, when said 7-alkoxycarbonyl-6,8-dimethyl-4-(α-halogeno-α-substituted methyl)-1-phthalazone is 7-alkoxycarbonyl-6,8-dimethyl-1-phthalazone-4-α-halogenoacetic acid, reacting it with a carboxylic acid salt such as sodium acetate and simultaneously decarboxylating the acyloxylated compound and then hydrolyzing the decarboxylated product or firstly decarboxylating the 1-phthalazone-4-α-halogenoacetic acid derivative, reacting the decarboxylated product with said carboxylic acid salt and then hydrolyzing the reaction product or when said 7-alkoxycarbonyl-6,8-dimethyl-4-(α-halogeno-α-substituted methyl)-1-phthalazone is 7-alkoxycarbonyl-4-(α-carbamoyl-α-halogenomethyl-6,8-dimethyl-1-phthalazone, reacting it with said carboxylic acid salt and then hydrolyzing and decarboxylating the acyloxylated compound simultaneously. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5254663-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5237062-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007238853-A1 |
| priorityDate | 1979-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 260.