http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4459300-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-46 |
| filingDate | 1982-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1984-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d24d2f99a2a70819fbe35d193b6c3e4d |
| publicationDate | 1984-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4459300-A |
| titleOfInvention | Pharmaceutically active aza-bicyclo benzamide derivatives |
| abstract | Compounds of formula (I) and pharmaceutically acceptable salts thereof: <IMAGE> (I) wherein: n, p and q independently are 0 to 2; R5 is hydrogen or C1-6 alkyl; R6 is C1-7 alkyl or a group -(CH2)sR7 where s is 0 to 2 and R7 is a C3-8 cycloalkyl group, or a group -(CH2)tR8 where t is 1 or 2 and R8 is C2-5 alkenyl or a phenyl group optionally substituted by one or two substituents selected from C1-6 alkyl, C1-4 alkoxy, trifluoromethyl and halogen, or a thienyl group; R12 is C1-6 alkylsulphonyl; and either R1 is C1-6 alkoxy or C1-6 alkylthio; and one of R2 and R11 is hydrogen and the other is C1-6 alkoxy, C1-6 alkyl or hydroxy; or R1 and R2 together are C1-3 alkylenedioxy; and R11 is hydrogen, halogen, CF3, C1-6 alkoxy, hydroxy, nitro, C1-7 acyl, amino, C1-7 acylamino, aminocarbonyl optionally substituted by one or two C1-6 alkyl, C3-8 cycloalkyl, C3-8 cycloalkyl C1-4 alkyl, phenyl or phenyl C1-4 alkyl groups any of which phenyl moieties may be substituted by one or more halogen, trifluoromethyl, C1-6 alkoxy or nitro groups or N-disubstituted by C4-6 polymethylene, having useful pharmacological activity, e.g. in the treatment of impaired gastric motility, a process for their preparation and their use. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4910207-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5017582-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4803199-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4797406-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5001133-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4588735-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6297018-B1 |
| priorityDate | 1981-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 319.