| abstract |
Aminoacid and peptide derivatives of the formula: A-NH-R1-CO]x[NH-R2-CO]y NH-R4-COOH in which A, R1, R2, x and y have the meanings specified in claim 1 for formula I, and R4 is a residue of an alpha -aminoacid which, when A is 4-allyloxy-3-chloro-phenylacetyl and x and y are 0, contains at least 2 carbon atoms, and their physiologically acceptable salts and lower alkyl ester. These compounds and 4-allyloxy-3-chloro-phenylacetylglycine have anti-inflammatory activity and pharmaceutical compositions containing them are described. |