| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9cb217f83556ce2a418344c2d485415 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-845
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-885
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-02 |
| filingDate |
1982-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1984-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2935deb29a29d452423b72b63ff77c0f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f20c3f5e939e9e97aba52e61ebc84024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed77c90debb74b1f37ad3db76b2858cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_108e440bde3c0c32ca4207bd89fcaef5 |
| publicationDate |
1984-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4443548-A |
| titleOfInvention |
Process for preparing L-α-methylphenyl alanines |
| abstract |
Biochemical optical resolution of DL- alpha -methylphenyl alanines in which DL- alpha -methylphenyl alanine amides are interacted with the culture products, or their treated products, of a microorganism capable of producing amidase is described. L- alpha -methylphenyl alanines having the general formula (I): <IMAGE> [I] wherein R1 and R2 may be independently a hydrogen atom or lower alkyl groups, or R1 and R2 may be alkylene groups combined together to form 5 through 8-membered rings is produced by the steps of: (a) making a DL- alpha -methylphenyl alanine amide having the general formula (II): <IMAGE> [II] wherein R1 and R2 are the same as defined above, interact with the culture product of a microorganism capable of producing enzyme catalyzing the hydrolysis of L-isomer of DL- alpha -methylphenyl alanine amides or the treated product thereof, whereby asymmetric hydrolysis of an L- alpha -methylphenyl alanine amide is effected; and (b) separating the resultant L- alpha -methylphenyl alanines from the hydrolysis mixture. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5283193-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010272756-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5215897-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5238828-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005123932-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007190076-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5248608-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4568641-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5766918-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4565782-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4812403-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8404250-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7871627-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005123932-A3 |
| priorityDate |
1981-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |