http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4443453-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fb3689bb224dbbee5f993de522c694e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
filingDate | 1981-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1984-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36de48a48b399448e51d60e11fa50616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba3ed66602525f8b773e399250d620a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc73c8ba2bec122bd6bb0e9e0f9d29fe |
publicationDate | 1984-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4443453-A |
titleOfInvention | Quinoline derivatives, pharmaceutical compositions containing such compounds, and methods for treating cardiovascular conditions with them |
abstract | The invention is concerned with novel quinoline derivatives of the formula <IMAGE> 1 or a salt thereof, in which A-B is -CH2-CH2-, -CHOH-CH2-, -CH2-CHOH-, -CH2-C(O)-, -C(NOR4)-CH2- or -CH2-C(NOR4)-, R1 is hydrogen, hydroxy or lower alkoxy, R2 is lower alkyl, R3 is ethyl or vinyl, R4 is lower alkyl, whereby the substituents at the 3- and 4-position of the piperidine ring are in the cis-position. The compounds of the formula may be in the form of the optically active enantiomers and/or their therapeutically acceptable salts. Furthermore the invention provides pharmaceutical compositions possessing cardiovascular activities in which as active compound at least a compound of the above formula is used. Methods for the preparation of the pharmaceutical compositions and of the active compounds are also included by the invention. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4613607-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7135483-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7304053-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004132722-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7476680-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006223853-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7789311-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7793846-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002099215-A1 |
priorityDate | 1980-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.