http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4438116-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-44 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-38 |
filingDate | 1981-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1984-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ed546781282411cbf287b9182e36ea9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f67d927d30bb6880e6f47faa6c349388 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a032b997d1cdad433e536cc2f03691fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4244002b2bc436201ae125b8c20736d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5c73447565e4d1caeba2f4b6f0ae9eb |
publicationDate | 1984-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4438116-A |
titleOfInvention | Quinoxalinyloxy-amino-propanol compounds with blood pressure lowering and β-blocking properties, their use and pharmaceutical compositions containing them |
abstract | An aminopropanol compound of the formula <IMAGE> wherein R1 and R2 are individually selected from hydrogen and lower alkyl; or R1 and R2 together represent an alkylene radical; R3 is hydrogen or acyl; A is one of the following structures <IMAGE> wherein R4 is hydrogen or lower alkyl optionally substituted by hydroxyl halogen and lower alkylthio; and R5 and R6 are individually selected from lower alkyl; B is alkylamino which optionally carries a phenyl and a phenoxy radical optionally substituted by at at least one of halogen, hydroxyl or lower alkyl, lower acyl, lower alkylthio, acylamino, aminocarbonyl, lower alkoxy, lower alkenyloxy, phenoxy, lower alkenyl, lower alkylsulphonyl, lower alkylsulphinyl or haloalkyl; or B is an aryl- or heteroaryloxymethylpiperidine radical optionally substituted by at least one of halogen hydroxyl or lower alkyl, hydroxyl alkyl or carboxamido alkyl, or by lower alkoxy, lower acyl, amino, carboxamido, lower alkylcarbonylamido or lower alkylsulphonylamino; and the pharmacologically acceptable salts thereof, are outstandingly effective beta blockers and blood-pressure depressants. |
priorityDate | 1979-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 203.