| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17439c4f66e8a64aaba82d323410e9c9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0478 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate |
1981-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1984-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dfe542db9992861694430af1462be5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddea886e38f9a8b622e83a1f4e8ea116
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec19b0790a391b7617fca3d5c3542eea |
| publicationDate |
1984-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4427647-A |
| titleOfInvention |
Method and reagent for making a radiopharmaceutical composition based on pertechnetate |
| abstract |
A method of making a radiopharmaceutical composition by mixing an aqueous solution of pertechnetate with a reducing agent comprising tin metal or stannous ion to reduce the pertechnetate and a complexing agent to form a complex with the reduced technetium, is characterized by incorporating nitrate and/or nitrite in an amount to diminish oxidation of Sn2+to Sn4+, and hence to prevent re-oxidation of technetium to pertechnetate, during preparation and storage of the complex. Nitrate and nitrite are superior to organic antioxidants previously proposed. A reagent for the purpose comprises the reducing agent, the complexing agent and the nitrate and/or nitrite usually in a sterile freeze-dried state. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6359119-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4666698-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9320691-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4707353-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9530443-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005276755-A1 |
| priorityDate |
1980-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |