| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b919a09598a02c07e8429b1441b76e1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-58 |
| filingDate |
1982-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1983-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2879febce0b8e0f82bbeca4e92a2c7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9de1e9bdf896ed768dacd7b1f1803ae |
| publicationDate |
1983-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4422979-A |
| titleOfInvention |
Fluoro-substituted biphenylyl compounds and processes |
| abstract |
2-(2-Fluoro-4-biphenylyl)propionic acid is prepared from 2-amino-4-methylbiphenyl via a series of novel intermediates. In particular 2-amino-4-methylbiphenyl is converted to 2-fluoro-4-methylbiphenyl, the methyl group is brominated to form 2-fluoro-4-monobromomethylbiphenyl which is transformed into 2-(2-fluoro-4-biphenylyl)acetonitrile. This acetonitrile is then converted to flurbiprofen via the corresponding propionitrile or it may be converted into flurbiprofen via the intermediate ethyl-2-(2-fluoro-4-biphenylyl)-2-cyanopropionate. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6646003-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0671380-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100529157-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4721790-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5532386-A |
| priorityDate |
1980-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |