http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4418205-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06d8c020934d598ab148ecfc5241c309 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0041 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 |
filingDate | 1981-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1983-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38ec1b0cd0fa69291be9cfa239b8f0d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeb264fb7493a1ac250365dae9619213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f0f7d587afba8c43748958142222c3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b54ca60d0fad342b0191d35566c437ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc0259b5c310fe88b935ea9db6a3e65b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34d5138ccc0459996c3bf5af444e1733 |
publicationDate | 1983-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4418205-A |
titleOfInvention | 16-Amino-18,19,20-trinor-prostaglandin derivatives, and acid addition salts |
abstract | The invention relates to new 16-amino-18,19,20-trinor-prostaglandin derivatives of general formula I, having at C-17 a substituted or unsubstituted phenyl group, wherein C-15 and C-16 may have either S or R configuration, Y stands for a hydrogen atom or a lower alkyl group, W stands for a hydrogen atom, halogen atom, hydroxy group, lower alkyl or alkoxy group, and their acid addition salts. These compounds can be prepared by removing the ester group and the p-nitrobenzyloxycarbonyl protective group of a 9 alpha ,11 alpha ,15-trihydroxy-16-p-nitrobenzyloxycarbonylamido-17-phenyl-5-cis,13-tra ns-18,19,20-trinor-prostadienoic acid derivative of general formula XII-wherein C-15 and C-16 may have either S or R configuration, W is as defined above, and Y stands for a lower alkyl group-in an optional sequence with the limitation that in those compounds of general formula I where W is as defined above and Y stands for a lower alkyl group, solely the p-nitrobenzyloxycarbonyl group is removed, and the resulting product of general formula I is optionally converted with an organic or inorganic acid into a salt. The new prostaglandin derivatives of the invention have valuable therapeutical properties, and can be applied in cattle raising for estrus and birth synchronization, furthermore in the veterinary praxis for the treatment of sterility, chronic endometritis and pyometry. |
priorityDate | 1980-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.