abstract |
A pyridine derivative having the formula <IMAGE> wherein X2 and Y2 represents hydrogen atom or chlorine atom is produced by reacting a pyridine compound having the formula <IMAGE> wherein X1 and Y1 represent hydrogen atom or chlorine atom, with chlorine and anhydrous hydrogen fluoride by a vapor phase reaction in the presence of a catalyst at a temperature of 250 DEG to 600 DEG C. using as the catalyst a fluoride of a metal selected from the group consisting of copper, vanadium, tin, bismuth, zirconium, magnesium, barium, zinc, calcium, potassium and sodium. |