| abstract |
The invention relates to a method of preventing or treating cerebral insufficiency, which method comprises administering to a human being in need of such treatment, orally or rectally, a prophylactic or a therapeutically effective amount of a compound of the general formula I <IMAGE> wherein X1 is hydrogen, halogen having an atomic number up to 35, or is cyano, and X2 and Y together are an additional bond, or X1 and X2 together are the oxo radical and Y is hydrogen, or X1 is hydroxy and X2 and Y are hydrogen. Examples of suitable compounds are 10,11-dihyro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide and, in particular, carbamazepine (5H-dibenz[b,f]azepine-5-carboxamide). |