| abstract |
A method of treating androgen-related disorders in an animal which comprises administering to the animal dihydrotestosterone level decreasing amounts of a compound of formula (I): <IMAGE> (I) wherein R is H or F; R1 is selected from the group consisting of -H; straight or branched chain lower alkyl; hydroxyl; -OCOR3; and O-(C1-C6 alkyl); wherein R3 is -H, C1-C10 straight or branched chain alkyl group, phenyl, phenyl alkylene having straight or branched chain C1-C6 alkylene, C5-C10 cycloalkyl or C6-C10 cycloalkyl alkylene; R2 is H2, methylene, ethylidene, alpha -CH3(H), beta -CH3(H), alpha -(OH)(H) or the acetonide derived from the 16 alpha ,17 alpha -dihydroxy derivative, and n is 1 or 2. |