http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4396613-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 |
| filingDate | 1981-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35c945494f1ac931825e71f9cc0c11b8 |
| publicationDate | 1983-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4396613-A |
| titleOfInvention | 23-Ester derivatives of DMT and method of using same |
| abstract | 23-Ester derivatives of demycinosyltylosin (DMT) of the formula: <IMAGE> 1 wherein R is selected from hydrogen, optionally substituted C1-C5-alkanoyl or optionally substituted benzoyl, phenylacetyl, or phenylpropionyl; and R1 is an acyl group selected from: <IMAGE> +TR <IMAGE> p is 0 or 1; m and n are integers from 0 to 4; R2 is hydrogen, halo, C1-C4-alkyl, C3-C8-cycloalkyl, phenyl, C5-C8-cycloalkenyl, naphthyl, indenyl, tetralinyl, decalinyl, adamantyl, cinnoxacinyl, a monocyclic heterocyclic ring system comprising 3 to 8 atoms or a bicyclic heterocyclic ring system comprising 6 to 11 atoms, provided that at least 1 atom of the ring system is carbon and at least 1 atom of the ring system is a heteroatom selected from O, N, and S; and wherein R2 and the connecting alkyl groups -(CH2)m- and -(CH2)n- are optionally substituted by one or two halo, methyl, ethyl, methoxy, amino, N-protected-amino, methylamino, dimethylamino, nitro, acetoxy, acetamido, azido, carbomethoxy, carboxamido, cyano, or hydroxyl groups, provided that, if the substituent is other than halo or alkyl, there can be no more than one substituent on any connecting -CH2- group; X is O, S, -NH-, -N(CH3)-, -C 3BOND C-, -CH=CH-, -C(CH3)=CH-, -CH=C(CH3)- or -C(CH3)=C(CH3)-; R3 and R4 are C1-C5-alkyl or optionally substituted phenyl or benzyl; and salts thereof are useful antibiotics or intermediates to antibiotics. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4851518-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4629786-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5511558-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4463171-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4575496-A |
| priorityDate | 1981-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 192.