Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 |
filingDate |
1981-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1983-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaa159d02dbda495eea6830f975db186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9925541794ffa84711b9ccfdaa03a954 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57d16d04ab858b6cb8ff662fea23dad5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8e96bb7177c75c0cbebe34b33a2e4c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59ffc6887150183186124192777f9366 |
publicationDate |
1983-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4390535-A |
titleOfInvention |
Antimicrobial 7-(α-acylamino-α-arylacetamido)-3-(substituted methyl)cephalosporin compounds |
abstract |
Compounds of the formula ##STR1## wherein R 1 is hydrogen or a (C 1 -C 4 ) alkyl group, X is a straight or branched chain C 1 -C 4 alkylene group and R 2 is a carboxyl group or a sulfo group; and the pharmaceutically acceptable salts thereof exhibit strong inhibitory activities against a wide variety of Gram-positive and Gram-negative bacteria including Psendomonas aeruginosa, indolepositive Proteus and Enterobacter aerogenes, and also have an increased and prolonged serum level in a living body. The compounds are therefore useful as antibacterial agents for the treatment of infectious diseases caused by Gram-positive and Gram-negative bacteria. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4880796-A |
priorityDate |
1980-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |