| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdaa64756184e715af6cb25ebc318917 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-215 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065 |
| filingDate |
1980-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1983-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1910a4565104c81941b03c9d41ce948
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a542bc59f0b3197c5032240ada5eb3a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49f89ffba5c1b8d20ea82eb594d3c556
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79faad768228714de6353f20f9120c49 |
| publicationDate |
1983-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4390526-A |
| titleOfInvention |
Pharmaceutical agents for the treatment of sickle cell disease |
| abstract |
The present invention relates to novel compounds selected from R1-COO(CH2)n-R2 and <IMAGE> wherein R1 is selected from heterocyclic aromatic and hydrophobic naturally occuring and modified amino acids in the D- and in the L-form, and from peptides, wherein n is an integer of from 1 to 5 and R2 is selected from unsubstituted and substituted phenyl rings, and from heterocyclic rings, as well as to pharmaceutical compositions for preventing sickling of erythrocytes during sickle cell crisis and for desickling of sickle cells of patients afflicted by sickle cell disease, the active ingredient of which is a compound as defined above. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5177208-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5514718-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5108754-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9301169-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5472978-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5328927-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9301169-A3 |
| priorityDate |
1979-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |