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filingDate 1981-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1983-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1983-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4388465-A
titleOfInvention Preparation of phenoxy-azolyl-butanone derivatives
abstract In the preparation of a phenoxy-azolyl-butanone derivative of the formula ##STR1## in which X is a halogen atom, n Y is a hydrogen or halogen atom, and n Az is an imidazolyl radical or a 1,2,4-triazolyl radical, n wherein dichloropinacolin of the formula n n Cl.sub.2 CH--CO--C(CH.sub.3).sub.3 n n is reacted with an azole of the formula n n Az--H n n and a phenol of the formula ##STR2## in the presence of an acid-binding agent, the improvement which comprises carrying out the reaction in the presence of a water-immiscible organic solvent at a temperature between about 40° and 150° C., adding to the solvent at a temperature between about 0° and +80° C. a mineral acid, thereby to precipitate the mineral acid salt of the phenoxy-azolyl-butanone derivative, and separating such salt. Surprisingly the product does not hydrolyze when standing in contact with the mineral acid solution. The product is a known fungicide.
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