| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a09ca043d7e596facff1f44b746e2f4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-831
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-83 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate |
1980-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1983-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00b25503564983360de7c02f4fdd2b56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83f5e66d5b1955f6e35549771704b8f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39d916d945dec44e0adc1b789027a3e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a9965a188605ea1befef7c18db82dce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1825b9b168b050f30a3b1fca1be8458 |
| publicationDate |
1983-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4384993-A |
| titleOfInvention |
Method of the production of immunoglobulin having high content of monomer |
| abstract |
A method of the production of immunoglobulin having a high content of monomer from immunoglobulin-containing materials by a fractionation method, which comprises carrying out the fractionation in the presence of a water-soluble, basic nitrogen-containing organic compound having a dissociation constant (pKb) of 7 or less or an acid addition salt thereof, and thereby inhibiting by-production of undesirable aggregated molecules. The immunoglobulin has a high content of monomer and contains no or little aggregated molecules and hence can be used as a medicine in immune prophylaxis and immunotherapy without undesirable side effects and can be administered by intraveneous route, and further, is useful for the preparation of chemically treated immunoglobulin having a high content of monomer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6713058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6436401-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5122373-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4634417-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8400891-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02060481-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4597966-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6187309-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004265312-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8758747-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5219578-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5945098-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4732863-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6294171-B2 |
| priorityDate |
1980-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |