http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4377570-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 |
| filingDate | 1980-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1983-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df8fb6bda7277ae5a2e8cc551fdcd3c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf4e66069be60543a9e62f1c2226c3e8 |
| publicationDate | 1983-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4377570-A |
| titleOfInvention | Immunologically active dipeptidyl saccharides and methods of preparation |
| abstract | 2-Amino-2-deoxy-glycoses of the general structural formula: <IMAGE> wherein R1 is hydrogen, alkyl (1-7C), substituted alkyl (1-7C), phenyl, substituted phenyl, benzyl, or substituted benzyl; R2 is alkyl, substituted alkyl, phenyl, or substituted phenyl; R3 is H or lower alkyl (1-10C) with the proviso that when the aminoglycose has the 2-amino-2-deoxy-D-glucose configuration, R3 cannot be H; R4 and R5 are same or different and are H, aliphatic or aromatic acyl (2-21C) or substituted acyl (2-21C); R6 is H, or R6-R7 together is -CH2-CH2-CH2-, R7 is H, alkyl (1-7C), hydroxymethyl, mercaptomethyl, benzyl, or substituted benzyl; R8 and R9 each is carboxyl, esterified carboxyl (1-7C), amidated carboxyl, or mono- or di-alkyl-(1-3C)-amidated carboxyl; provided that when R3 is lower alkyl, the stereochemistry at asymmetric center I can be either D or L, but that when the aminoglycose has the 2-amino-2-deoxy-D-glucose configuration, the stereochemistry at I cannot be D; when R7 is not H, the stereochemistry at asymmetric center II is either L or D; and the stereochemistry at asymmetric center III is D. These compounds possess immunostimulatory properties. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5589463-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4868155-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5334583-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6649746-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5189017-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5561111-A |
| priorityDate | 1979-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 282.