abstract |
The invention relates to chroman derivatives of the general formula <IMAGE> wherein R1 is hydrogen, lower alkyl, substituted phenyl, phenyl, phenyl-lower alkyl, substituted phenyl-lower alkyl or lower alkyl-amino-lower alkyl; R2 is <IMAGE> <IMAGE> <IMAGE> <IMAGE> R3, R4, R5 and R6 each is independently selected from hydrogen, hydroxy, amino, -o-acyl, -o-lower alkyl; <IMAGE> halogen, lower alkyl, or halo substituted lower alkyl; and salts and hydrates thereof. These compounds are useful as anti-inflammatory agents; for inhibition of blood platelet aggregation, as antiallergy and as antihypertensive agents. |