http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4353826-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79751aeaa9923745648e5ae7d9c35782 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 |
| filingDate | 1980-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1982-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34fa569a30f223a614bc34ad5b1b41c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c9476b905c793c72e91f6cf5a5c7315 |
| publicationDate | 1982-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4353826-A |
| titleOfInvention | Substituted rifamycins |
| abstract | Antibiotically active compounds derived from rifamycin S or from the corresponding hydroquinone, rifamycin SV, or from derivatives at least partially hydrogenated in positions 16, 17; 18, 19; 28, 29, such as the 16, 17; 18, 19-tetrahydro- or the 16, 17; 18, 19; 28, 29-hexahydro derivatives, which contain in position 3 a free or an aliphatically substituted amino group. The hydrocarbon radicals of the aliphatically substituted amino group can also be interrupted in their carbon chain by heteroatoms and/or be substituted by functional groups. A special group of these new compounds is represented by 3-amino derivatives as defined above, in which the amino group is a particular type of N-aza-cyclo-aliphatic radical unsubstituted by functional groups, and which has, in addition to the antibiotic action against sensitive microorganisms also an antibacterial activity against certain types of resistant microorganisms. Another special group is represented by 3-amino derivatives as defined above, in which the amino group is a particular type of a 4R-1-piperazinyl radical, in which R is a hydrocarbon radical; they have a special high antituberculosis action, while having very low toxicity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005248908-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007096703-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10216719-B4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5147870-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5003070-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4916126-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0303571-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4876258-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010019511-A2 |
| priorityDate | 1965-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 802.