http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4336396-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c2fa1eaecc61ff197e5f878accf96ad |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 |
| filingDate | 1980-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1982-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bf21b601a91fa9e1cae89be557f92df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_999b5a73758f0f30fc7c1e577db2fac2 |
| publicationDate | 1982-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4336396-A |
| titleOfInvention | Process for the preparation of 4-[2-(dimethylamino)-ethoxy]2-methyl-5-(1-methylethyl)-phenol esters and their salts |
| abstract | This invention relates to a process for the preparation of 4-[2-(dimethylamino)-ethoxy]-2-methyl-5-(1-methylethyl)-phenol esters (I) and their salts with organic and inorganic acids comprising the reaction of thymol with a salt of an 1-halo-dimethylaminoethane to obtain ethylamine-N,N-dimethyl-2-(thymyloxy) (II), the subsequent reaction of (II) with an acylating agent according to the Friedel and Kraft reaction to obtain 4-[2-(dimethylamino)-ethoxy]-2-methyl-5-(1-methylethyl)-1-acyl-benzene (III) and the oxidation of (III) to obtain the products (I) which, if desired, may be transformed in their salts with organic or inorganic acids. n This process allows to obtain the products (I) in high quality and quantity without isolating any intermediate product. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4818772-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5451609-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6730691-B1 |
| priorityDate | 1979-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.