http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4330553-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-937 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-937 |
| filingDate | 1980-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1982-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c889f531a94af0dd5bd24af7b8e4c1f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba4ac56d8e2c27153f99e321c19ba85d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4e95000f6ac36fe153f184bd256371b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1609522374983f00c289842057b9a26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_beb9724c748d03e15cc1dcd2a7344bef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e226ce8f184ef73e3345a29856779be4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a97ea1aca1b497b31458fa995f64bc4 |
| publicationDate | 1982-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4330553-A |
| titleOfInvention | 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same |
| abstract | New PGI2 derivatives and a process for their preparation are disclosed of the formula (I) <IMAGE> wherein Q is hydrogen, a pharmacologically acceptable cation, or lower alkyl; A is cis or trans -CH=CH-, -C 3BOND C-, or -CH2-CH2-; R13 is hydrogen or a C1 to C4 alkanoyl or is a blockinggroup of the formula R7R8R9Si or <IMAGE> wherein R7, R8 and R9 are the same or different and can be straight or branched chain alkyl groups having 1 to 4 carbon atoms and R10 and R11 are the same or different and can be hydrogen or methyl, and R12 represents methyl or ethyl, or is tetrahydropyran-2-yl; R4 is hydrogen or lower alkyl inthe alpha or beta steric position; R1 and R2 are each hydrogen or lower alkyl; Y is methylene, oxygen or an -NH- group; and R3 is lower alkyl or phenyl which can be monosubstituted phenyl. The compounds are useful as antiaggregation or thrombus-dissolving agents, stomach juice secretion inhibiting agents and antiasthmatic agents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4735965-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4520018-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0163905-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5104861-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4466969-A |
| priorityDate | 1979-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.