http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4322350-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0cb7734bc2e5840db630f0ae7c29684 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-04 |
filingDate | 1978-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1982-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d252c715f83b861462ede0df56d9903 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d874615518defbdbc07e1a73be09a07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d448172097ad08cd00dd110b40aa591 |
publicationDate | 1982-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4322350-A |
titleOfInvention | Process for the synthesis of leurosine and of its derivatives |
abstract | A process for the preparation of a compound of formula (V) and salts thereof ##STR1## wherein R 1 is selected from the group consisting of a hydrogen atom, an alkyl radical, a formyl radical and an acyl radical; n R 2 is selected from the group consisting of an alkoxycarbonyl radical, a hydrazide radical, an acetamido radical, a hydroxymethyl radical, and an alkanoyloxy methyl radical n and n R 3 and R 4 are the same or different and each is selected from the group consisting of a hydrogen atom, a hydroxyl radical and an alkanoyloxyl radical; n which comprises the step of treating a compound of formula IV ##STR2## wherein R 1 , R 2 , R 3 and R 4 are as previously defined with at least one oxidising agent selected from the group consisting of oxidising metal salts, air and oxygen. n The above compounds are useful due to their antitumoral activity, and to their use as intermediates of other antitumor drugs. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100364996-C http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4746665-A |
priorityDate | 1977-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.