abstract |
1-Phenethylimidazole compounds of the formula: <IMAGE> wherein R1 and R2 are independently hydrogen or halogen, Z is a mono or disubstituted phenyl moiety of the formula: <IMAGE> or a 2 or 3-thienyl moiety of formula: <IMAGE> wherein R3 and R4 are independently hydrogen, halogen, (lower) alkyl, or trifluoromethyl, with the proviso that R3 and R4 can not both be trifluoromethyl and the antimicrobial acid addition salts thereof are useful as antifungal and antibacterial agents. |