Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 |
filingDate |
1979-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1981-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3afb265183c04780919d528f15c5b97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29b4e505b7ff78a711546ae1dd4df1b2 |
publicationDate |
1981-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4301250-A |
titleOfInvention |
Method of producing hepatitis B surface antigen |
abstract |
Hepatitis B surface antigen (HBsAg) is produced in vitro in high titer and purity from tissue cultures of cells that shed HBsAg by growing the cells with a first incubation at elevated temperature followed by a second incubation at a lower elevated temperature. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5498537-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0133599-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4416986-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0133599-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4758507-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4612283-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4714613-A |
priorityDate |
1979-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |