http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4299992-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f68254c2256a29224bb518f200d45ce9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-34 |
| filingDate | 1980-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1981-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd349a86c9c012eb05f5e961be94df3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5e664e8b5c732b441a104177cc34c60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_789a042048c64a74c1dae1a80863efb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb815cd49b7a0ace40112cb4ef629f20 |
| publicationDate | 1981-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4299992-A |
| titleOfInvention | Process for the selective hydroxymethylation of nitrotoluenes |
| abstract | The invention relates to a new process for the selective hydroxymethylation of substituted ortho- or paranitrotoluenes of the general formula (I) ##STR1## in order to prepare nitrophenylalkanols of the general formula (II) ##STR2## In the above formulae the nitro group is attached to the benzene ring in ortho or para position related to the methyl group or the hydroxyalkyl side chain, respectively, X stands for hydrogen, fluorine or an alkyl, alkoxy or nitro group, and n is 1, 2 or 3. n According to the process of the invention the starting substance is hydroxymethylated with an excess of formaldehyde at a temperature above room temperature in dimethyl formamide and in the presence of a strong base. The reaction is performed in dimethyl formamide containing 0.1 to 1% by weight of water, and the reaction is directed to the formation of the required end-product by properly adjusting the temperature and the amount of formaldehyde and the base with respect to the starting compound of the general formula (I). n In this way the required end-products can be prepared selectively also on an industrial scale. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4497966-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5399790-A |
| priorityDate | 1979-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.