abstract |
Corticosteroid formulations in the form of a lipophilic stick are provided which are used as anti-inflammatory agents; the lipophilic stick includes the corticosteroid, such as halcinonide or triamcinolone acetonide, dissolved in an oleaginous solvent which is miscible with the other stick ingredients, which solvents include isostearyl alcohol, dibutyl sebacate, castor oil and/or mineral oil, one or more waxes to provide body and stiffness, and an anti-microbial agent to prevent growth and eliminate the spreading of microbes on the surface of the stick, such as propylene glycol or 1,3-butylene glycol. |