| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D9-02 |
| filingDate |
1980-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1981-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd38a9cd877dbcf5350d358a9ae7b582 |
| publicationDate |
1981-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4298732-A |
| titleOfInvention |
Crystallization process |
| abstract |
A process for the preparation of crystalline sodium cefuroxime (the sodium salt of (6R,7R)-3-carbamoyloxymethyl-7-[(Z)-2-(fur-2-yl)-2-methoxyimino-acetamido]ceph-3-em-4-carboxylic acid) which comprises adding an aqueous solution of sodium cefuroxime and an aqueous solution containing sodium ions to an aqueous crystallizing medium containing a seeding amount of solid sodium cefuroxime and recovering crystalline sodium cefuroxime from the crystalline medium. The process enables the production of crystalline sodium cefuroxime on an industrial scale in a condition of sufficient sterility, purity and solid state stability for use in pharmaceutical preparations. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112979082-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100396464-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101475579-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4775750-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103102357-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103374019-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102617604-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004214752-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7842791-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103102357-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100384853-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102295653-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103374019-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112979082-B |
| priorityDate |
1978-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |