| abstract |
The present invention relates to a process for obtaining low molecular weight heparins endowed with pharmacological and therapeutic properties of outstanding interest, starting from normal heparin. n The said process is characterized in that it comprises the following steps: n (a) acidification of normal heparin to obtain heparinic acid, n (b) depolymerization of said heparinic acid by heating in autoclave in the presence of peroxides, to obtain a low molecular weight heparamine, n (c) sulphation of said heparamine to obtain the corresponding low molecular weight heparin. n A further object of the invention is the low molecular weight heparins, or LMW heparins, so obtained, and their utilization in the field of therapeutics. |