abstract |
Disclosed are 7,7-dimethyl-4,5 alpha -epoxy-morphinan-6-one compounds characterized by the formula: <IMAGE> wherein R is H or CH3, R1 is H, CH3 or CH2CH3 and R2 is cyclopropylmethyl or cyclobutylmethyl. Particular compounds circumscribed by the foregoing formula are useful as analgesics, narcotic antagonists or mixed analgesics/narcotic antagonists. |