abstract |
The invention relates to novel dibenzo[1,2;5,6]cyclohepta pyridine or -pyrrole derivatives, dibenzo[2,3;6,7]oxepino pyridine or pyrrole derivatives, dibenzo[2,3;6,7]thiepino pyridine or pyrrole derivatives and dibenzo[b,f]pyrido or pyrrolo azepine derivatives of general formula: ##STR1## as well as the pharmaceutically acceptable salts and nitrogen oxides thereof, wherein n R 1 , R 2 , R 3 and R 4 each represent hydrogen, hydroxy, halogen, an alkyl (1-6 C) group, an alkoxy or alkylthio group in which the alkyl group contains 1-6 C-atoms, or a trifluoromethyl group, n R 5 represents hydrogen, an alkyl group with 1-6 carbon atoms or an aralkyl group with 7-10 carbon atoms, n m is the number 1 or 2, n X represents oxygen, sulphur, the group ##STR2## or the group --CH 2 -- and R 6 represents hydrogen or a lower alkyl group (1-4 C), n having CNS-depressant activity and excellent antihistamine and antiserotonin activities. |