abstract |
A blood pressure reducing composition which inhibits renin in vivo which composition has the peptide structure Z-His-Pro-Phe-His-X-X-Val-Tyr-Y wherein the xs are the same or different and are phenylalanine, a chlorinated phenylalanine or tyrosine, Y is a charged amino acid and Z is proline or polyproline having up to 5 prolyl residues. |