http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4256753-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d6256baf554e46784d8daa478a2ddc6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 |
filingDate | 1979-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1981-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dad50da82e193beec3fb39a40afea230 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8d05f530133554fefe04316712ccb84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_226a07b00352c45bc1dc3d9501d91b4c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af9334a83d79250b2610712e2e4b8a58 |
publicationDate | 1981-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4256753-A |
titleOfInvention | 4-(2-Pyridylamino)phenylacetic acid derivatives |
abstract | Novel 4-(2'-pyridylamino)phenylacetic acid derivatives of the formula: <IMAGE> wherein R1 is hydrogen, a halogen, a lower alkyl having 1 to 3 carbon atoms, or nitro, R2 is hydrogen, a halogen, or a lower alkyl having 1 to 3 carbon atoms, R3 is hydrogen, a halogen, or a lower alkyl having 1 to 3 carbon atoms, R4 is hydrogen or a lower alkyl having 1 to 3 carbon atoms, R5 is hydrogen or -CH2CH2OR6 wherein R6 is a lower alkyl having 2 or 3 carbon atoms and being substituted with 1 or 2 hydroxy groups, provided that R1 or R2 is not 4-halogen, or pharmaceutically acceptable salts thereof, and a process for the preparation thereof, pharmaceutical composition of said compounds, and a method of using said compounds as anti-inflammatory and analgesic agents. They have excellent anti-inflammatory and analgesic activities with an extremely weak ulcerogenicity in the gastrointestinal tract. Some of the compounds have superior inhibitory activity against chronic inflammation mediated by cellular immunity. |
priorityDate | 1978-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.