abstract |
The invention disclosed herein relates to pharmacologically active prostaglandin derivatives of the E, F, or A series having on the terminal methylene carbon of the alpha chain a substituent selected from the group consisting of: <IMAGE> wherein R is an alkyl group and R15 is C1-C4 alkyl, di-C1-C4-alkylamino, C1-C4 alkoxy, and phenyl or phenyl substituted with one or more substituents from the group consisting of C1-C4, OR, SR, F, or Cl wherein R is as previously defined. |